Article
polyhomeotic controls engrailed expression and the hedgehog signaling pathway in imaginal discs.
Mechanisms of development - 1 Jul 2000
Randsholt N B, Maschat F, Santamaria P
Abstract excerpt
Polycomb group (PcG) genes maintain cell identities during development in insects and mammals and their products are required in many developmental pathways. These include limb morphogenesis in Drosophila melanogaster, since PcG genes interact with identity and pattern specifying genes in imaginal discs and clones of polyhomeotic (ph) null cells induce abnormal limb patterning. Such clones are associated with...
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