Article
A mathematical model of rat ascending Henle limb. III. Tubular function.
American journal of physiology. Renal physiology - 1 Mar 2010
Weinstein Alan M
Abstract excerpt
K+ plays a catalytic role in AHL Na+ reabsorption via Na+-K+-2Cl- cotransporter (NKCC2), recycling across luminal K+ channels, so that luminal K+ is not depleted. Based on models of the ascending Henle limb (AHL) epithelium, it has been hypothesized that NH4+ may also catalyze luminal Na+ uptake. This hypothesis requires that luminal NH4+ not be depleted, implying replenishment via either direct secretion of...
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