Article
Ammonia and urea permeability of mammalian aquaporins.
Handbook of experimental pharmacology - 1 Jan 2009
Litman Thomas, Søgaard Rikke, Zeuthen Thomas
Abstract excerpt
The human aquaporins,AQP3,AQP7, AQP8,AQP9, and possibly AQP10, are permeable to ammonia, and AQP7, AQP9, and possibly AQP3, are permeable to urea. In humans, these aquaporins supplement the ammonia transport of the Rhesus (Rh) proteins and the urea transporters (UTs). The mechanism by which ammon...
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