Article
[Effect of KRAS mutation on efficacy of Cetuximab combined with chemotherapy in advanced colorectal cancer patients].
Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery - 1 Nov 2009
Pu Xing-xiang, Deng Yan-hong, Xu Fei, Xiao Jian, Guo Hong-qiang, Huang He, Tian Ying, He You-jian, Lin Tong-yu
Abstract excerpt
OBJECTIVE: To explore the relationship between KRAS gene status and efficacy of Cetuximab (C225) combined with chemotherapy on advanced colorectal cancer in Chinese patients, and to evaluate the safety of C225. METHODS: From May 2006 to March 2009, 81 patients with advanced colorectal cancer received Cetuximab combined with chemotherapy were enrolled in this study. The rate of KRAS mutation and the relationship...
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