Article
[Cetuximab for patients with metastatic colorectal cancer-from the result of recent clinical trials].
Gan to kagaku ryoho. Cancer & chemotherapy - 1 May 2010
Ariyama Hiroshi, Kusaba Hitoshi, Baba Eiji
Abstract excerpt
Cetuximab is a monoclonal antibody that inhibits human epidermal growth factor receptor, and was approved for metastatic advanced colorectal cancer (mCRC) in 2008 in Japan. Evidences confirming the efficacy of cetuximab have been accumulated in western countries. As the first- and second-line therapy, cetuximab plus chemotherapy showed longer survival compared with chemotherapy alone. As a third-line...
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