Article
Impact of second-line and later cetuximab-containing therapy and KRAS genotypes in patients with metastatic colorectal cancer: a multicenter study in Japan.
Surgery today - 1 Aug 2014
Saeki Hiroshi, Emi Yasunori, Kumashiro Ryuichi, Otsu Hajime, Kawano Hiroyuki, Ando Koji, Ida Satoshi, Kimura Yasue, Tokunaga Eriko, Oki Eiji, Morita Masaru, Shimokawa Mototsugu, Maehara Yoshihiko
Abstract excerpt
PURPOSES: This retrospective study evaluated the treatment outcomes and clinical relevance of the KRAS mutation status in Japanese metastatic colorectal cancer patients treated with second-line and later cetuximab-containing therapy. METHODS: The subjects comprised 65 patients with metastatic colorectal cancer who received cetuximab-containing therapy. At the start of cetuximab-containing therapy, the KRAS...
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