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Article

Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer.

The New England journal of medicine - 2 Apr 2009

Van Cutsem Eric, Köhne Claus-Henning, Hitre Erika, Zaluski Jerzy, Chang Chien Chung-Rong, Makhson Anatoly, D'Haens Geert, Pintér Tamás, Lim Robert, Bodoky György, Roh Jae Kyung, Folprecht Gunnar, Ruff Paul, Stroh Christopher, Tejpar Sabine, Schlichting Michael, Nippgen Johannes, Rougier Philippe

Abstract excerpt

BACKGROUND: We investigated the efficacy of cetuximab plus irinotecan, fluorouracil, and leucovorin (FOLFIRI) as first-line treatment for metastatic colorectal cancer and sought associations between the mutation status of the KRAS gene in tumors and clinical response to cetuximab. METHODS: We ran...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19339720
DOI: 10.1056/NEJMoa0805019

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19339720-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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