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Article

The role of KRAS mutations in predicting the efficacy of cetuximab-plus-irinotecan therapy in irinotecan-refractory Korean metastatic colorectal cancer patients.

Oncology - 1 Jan 2009

Sohn Byeong Seok, Kim Tae Won, Lee Jae-Lyun, Ryu Min-Hee, Chang Heung Moon, Kang Yoon-Koo, Park Hyo Suk, Na Young-Soon, Jang Se Jin, Kim Jin Cheon, Lee Jung Shin

Abstract excerpt

OBJECTIVE: This study evaluated the clinical relevance of KRAS and BRAF mutational status in 66 irinotecan-refrac- tory Korean metastatic colorectal cancer (mCRC) patients treated with cetuximab-plus-irinotecan-based chemotherapy. METHODS: A total of 66 irinotecan-refractory mCRC patients treated with cetuximab-plus-irinotecan-based chemotherapy were included. Tumors were screened for KRAS mutations (codons 12...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19738388
DOI: 10.1159/000236046

Genes

KRAS
BRAF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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