Article
Timing of bone marrow cell delivery has minimal effects on cell viability and cardiac recovery after myocardial infarction.
Circulation. Cardiovascular imaging - 1 Jan 2010
Swijnenburg Rutger-Jan, Govaert Johannes A, van der Bogt Koen E A, Pearl Jeremy I, Huang Mei, Stein William, Hoyt Grant, Vogel Hannes, Contag Christopher H, Robbins Robert C, Wu Joseph C
Abstract excerpt
BACKGROUND: Despite ongoing clinical trials, the optimal time for delivery of bone marrow mononuclear cells (BMCs) after myocardial infarction is unclear. We compared the viability and effects of transplanted BMCs on cardiac function in the acute and subacute inflammatory phases of myocardial infarction. METHODS AND RESULTS: The time course of acute inflammatory cell infiltration was quantified by FACS analysis...
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