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Article

Hypoxic preconditioning enhances the benefit of cardiac progenitor cell therapy for treatment of myocardial infarction by inducing CXCR4 expression.

Circulation research - 22 May 2009

Tang Yao Liang, Zhu Wuqiang, Cheng Min, Chen Lijuan, Zhang John, Sun Tao, Kishore Raj, Phillips M Ian, Losordo Douglas W, Qin Gangjian

Abstract excerpt

Myocardial infarction rapidly depletes the endogenous cardiac progenitor cell pool, and the inefficient recruitment of exogenously administered progenitor cells limits the effectiveness of cardiac cell therapy. Recent reports indicate that interactions between the CXC chemokine stromal cell-deriv...

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Source

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Identifiers

PMID: 19407239
DOI: 10.1161/CIRCRESAHA.109.197723
PMCID: PMC2756190

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19407239-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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