Article
Stem cell factor receptor induces progenitor and natural killer cell-mediated cardiac survival and repair after myocardial infarction.
Proceedings of the National Academy of Sciences of the United States of America - 14 Feb 2006
Ayach Bilal B, Yoshimitsu Makoto, Dawood Fayez, Sun Mei, Arab Sara, Chen Manyin, Higuchi Koji, Siatskas Christopher, Lee Paul, Lim Hilda, Zhang Jane, Cukerman Eva, Stanford William L, Medin Jeffrey A, Liu Peter P
Abstract excerpt
Inappropriate cardiac remodeling and repair after myocardial infarction (MI) predisposes to heart failure. Studies have reported on the potential for lineage negative, steel factor positive (c-kit+) bone marrow-derived hematopoetic stem/progenitor cells (HSPCs) to repair damaged myocardium through neovascularization and myogenesis. However, the precise contribution of the c-kit signaling pathway to the cardiac...
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