Article
No association between MTHFR C677T and serum uric acid levels among Japanese with ABCG2 126QQ and SLC22A12 258WW.
Nagoya journal of medical science - 1 Feb 2013
Hinohara Yukako, Naito Mariko, Okada Rieko, Yin Guan, Higashibata Takahiro, Tamura Takashi, Kawai Sayo, Morita Emi, Wakai Kenji, Matsuo Hirotaka, Mori Atsuyoshi, Hamajima Nobuyuki
Abstract excerpt
Several genome-wide association studies (GWAS) have revealed that single nucleotide polymorphisms (SNPs) of ABCG2 and SLC22A12 were strongly associated with serum uric acid (SUA), but those of methylene tetrahydrofolate reductase (MTHFR) were not. However, there were several studies indicating the association with MTHFR C677T polymorphism. This study examined the association with the polymorphism, taking into...
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