Article
Genetic variants of IL-6 and its receptor are not associated with schizophrenia in Taiwan.
Neuroscience letters - 14 Jan 2010
Liu Yu-Li, Liu Chih-Min, Fann Cathy Shen-Jang, Yang Wei Chih, Chen Ya-Hui, Tseng Li-Jung, Liu Shih-Kai, Hsieh Ming H, Hwang Tzung-Jeng, Chan Hung-Yu, Chen Jiann-Jyh, Chen Wei J, Hwu Hai-Gwo
Abstract excerpt
The pathophysiological process of schizophrenia is still unclear. The levels of interleukine-6 (IL-6) and its receptor, soluble IL-6R, have been reported to be elevated in the plasma and cerebrospinal fluid of schizophrenic patients. In this study, we tested the association of genetic variants of IL-6 and IL-6R with schizophrenia. Genotyping of three single nucleotide polymorphisms (SNP) for each IL-6 (IL-6-1,...
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