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Article

Interleukin-6 promoter polymorphism and plasma levels in patients with schizophrenia.

Tissue antigens - 1 Aug 2012

Zakharyan R, Petrek M, Arakelyan A, Mrazek F, Atshemyan S, Boyajyan A

Abstract excerpt

Schizophrenia is a severe psychiatric disease with inflammatory component. Several studies indicated the increased blood levels of proinflammatory interleukin-6 cytokine in schizophrenia. However, only limited studies explored the relationship between excess production and genetic variations of this cytokine in schizophrenia, and the results were controversial. Here, we investigated possible association of the...

Topics

Adult
Alleles
Enzyme-Linked Immunosorbent Assay
Female
Gene Frequency
Genetic Predisposition to Disease
Humans
Interleukin-6
Male
Middle Aged
Odds Ratio
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Promoter Regions, Genetic

Risk Factors

Schizophrenia

Source

Identifiers

PMID: 22571276
DOI: 10.1111/j.1399-0039.2012.01886.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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