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Article

Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer.

Gastroenterology - 1 Mar 2010

Smith J Joshua, Deane Natasha G, Wu Fei, Merchant Nipun B, Zhang Bing, Jiang Aixiang, Lu Pengcheng, Johnson J Chad, Schmidt Carl, Bailey Christina E, Eschrich Steven, Kis Christian, Levy Shawn, Washington M Kay, Heslin Martin J, Coffey Robert J, Yeatman Timothy J, Shyr Yu, Beauchamp R Daniel

Abstract excerpt

BACKGROUND & AIMS: Staging inadequately predicts metastatic risk in patients with colon cancer. We used a gene expression profile derived from invasive, murine colon cancer cells that were highly metastatic in an immunocompetent mouse model to identify patients with colon cancer at risk of recurrence. METHODS: This phase 1, exploratory biomarker study used 55 patients with colorectal cancer from Vanderbilt...

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Identifiers

PMID: 19914252
DOI: 10.1053/j.gastro.2009.11.005
PMCID: PMC3388775

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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