12-Gene Recurrence Score Assay Stratifies the Recurrence Risk in Stage II/III Colon Cancer With Surgery Alone: The SUNRISE Study.

doi:10.1200/JCO.2016.67.0414

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Article

12-Gene Recurrence Score Assay Stratifies the Recurrence Risk in Stage II/III Colon Cancer With Surgery Alone: The SUNRISE Study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Aug 2016

Yamanaka Takeharu, Oki Eiji, Yamazaki Kentaro, Yamaguchi Kensei, Muro Kei, Uetake Hiroyuki, Sato Takeo, Nishina Tomohiro, Ikeda Masataka, Kato Takeshi, Kanazawa Akiyoshi, Kusumoto Tetsuya, Chao Calvin, Lopatin Margarita, Krishnakumar Jayadevi, Bailey Helen, Akagi Kiwamu, Ochiai Atsushi, Ohtsu Atsushi, Ohashi Yasuo, Yoshino Takayuki

Abstract excerpt

PURPOSE: The 12-gene Recurrence Score assay has been validated in resected stage II colon cancer treated with or without chemotherapy and resected stage III disease treated with chemotherapy. This study evaluated the 12-gene Recurrence Score assay for stage II and III colon cancer without chemotherapy to reveal the natural course of recurrence risk in stage III disease. METHODS: A cohort-sampling design was used....

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PMID: 27325854
DOI: 10.1200/JCO.2016.67.0414

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