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Article

Delta-catenin is required for the maintenance of neural structure and function in mature cortex in vivo.

Neuron - 12 Nov 2009

Matter Cheryl, Pribadi Mochtar, Liu Xin, Trachtenberg Joshua T

Abstract excerpt

Delta-catenin is a brain-specific member of the adherens junction complex that localizes to the postsynaptic and dendritic compartments. This protein is likely critical for normal cognitive function; its hemizygous loss is linked to the severe mental retardation syndrome Cri-du-Chat and it directly interacts with presenilin-1 (PS1), the protein most frequently mutated in familial Alzheimer's disease. Here we...

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Identifiers

PMID: 19914181
DOI: 10.1016/j.neuron.2009.09.026
PMCID: PMC2840037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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