Article
Whole genome expression as a quantitative trait.
Biochemical Society transactions - 1 Dec 2009
Hardy John, Trabzuni Danyah, Ryten Mina
Abstract excerpt
Surprisingly, whole genome analyses of complex human neurological and psychiatric disorders have revealed that many genetic risk factors are likely to influence gene expression rather than alter protein sequences. Previous analyses of neurological diseases have shown that genetic variability in gene expression levels of deposited proteins influence disease risk. With this background, we have embarked on a...
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