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Article

Using gene expression to investigate the genetic basis of complex disorders.

Human molecular genetics - 15 Oct 2008

Nica Alexandra C, Dermitzakis Emmanouil T

Abstract excerpt

The identification of complex disease susceptibility loci through genome-wide association studies (GWAS) has recently become possible and is now a method of choice for investigating the genetic basis of complex traits. The number of results from such studies is constantly increasing but the challenge lying forward is to identify the biological context in which these statistically significant candidate variants...

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PMID: 18852201
DOI: 10.1093/hmg/ddn285
PMCID: PMC2570059

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