Article
Improvement of an ultrasensitive human immunodeficiency virus type 1 real-time reverse transcriptase-polymerase chain reaction targeting the long terminal repeat region.
Transfusion - 1 Mar 2010
Edelmann Anke, Kalus Ulrich, Oltmann Anke, Stein Angela, Unbehaun Anett, Drosten Christian, Krüger Detlev H, Hofmann Jörg
Abstract excerpt
BACKGROUND: Human immunodeficiency virus Type 1 (HIV-1) assays applying nucleic acid testing (NAT) rely on HIV-1 sequence-specific primers and probes. Their hybridization can be limited or abolished by genetic polymorphisms occurring in the target sequence. STUDY DESIGN AND METHODS: Blood donatio...
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