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A cluster of human immunodeficiency virus Type 1 recombinant form escaping detection by commercial genomic amplification assays

18 Nov 2010

Abstract excerpt

BACKGROUND: Nucleic acid testing (NAT)-based methods for the detection and quantification of human immunodeficiency virus Type 1 (HIV-1) RNA are used to increase transfusion safety and to diagnose and manage HIV-1-infected patients. We describe a novel HIV-1 recombinant form associated with lack of reactivity or substantial underestimation of viral load by commercial NAT assays. STUDY DESIGN AND METHODS: We...

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PMID: 21087286
DOI: 10.1111/j.1537-2995.2010.02942.x

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