Impact of HIV-1 genetic diversity on plasma HIV-1 RNA Quantification: usefulness of the Agence Nationale de Recherches sur le SIDA second-generation long terminal repeat-based real-time reverse transcriptase polymerase chain reaction test.

doi:10.1097/QAI.0b013e3180640cf5

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Article

Impact of HIV-1 genetic diversity on plasma HIV-1 RNA Quantification: usefulness of the Agence Nationale de Recherches sur le SIDA second-generation long terminal repeat-based real-time reverse transcriptase polymerase chain reaction test.

Journal of acquired immune deficiency syndromes (1999) - 1 Aug 2007

Rouet François, Chaix Marie-Laure, Nerrienet Eric, Ngo-Giang-Huong Nicole, Plantier Jean-Christophe, Burgard Marianne, Peeters Martine, Damond Florence, Ekouevi Didier Koumavi, Msellati Philippe, Ferradini Laurent, Rukobo Sandra, Maréchal Valérie, Schvachsa Nilda, Wakrim Lahcen, Rafalimanana Christian, Rakotoambinina Benjamin, Viard Jean-Paul, Seigneurin Jean-Marie, Rouzioux Christine

Abstract excerpt

The high genetic diversity of HIV-1 has a major impact on the quantification of plasma HIV-1 RNA, representing an increasingly difficult challenge. A total of 898 plasma specimens positive for HIV-1 RNA by commercial assays (Amplicor v1.5; Roche Diagnostic Systems, Alameda, CA or Versant v3.0; Bayer Diagnostics, Emeryville, CA) were tested using the Agence Nationale de Recherches sur le SIDA second-generation...

Topics

Genetic Variation
HIV Infections
HIV Long Terminal Repeat
HIV-1
Humans
Molecular Epidemiology
RNA, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Reagent Kits, Diagnostic

Reverse Transcriptase Polymerase Chain Reaction

Viral Load

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Open in PubMed

Identifiers

PMID: 17468666
DOI: 10.1097/QAI.0b013e3180640cf5

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