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Article

Genome-wide identification of somatic aberrations from paired normal-tumor samples.

PloS one - 1 Jan 2014

Li Ao, Liu Yuanning, Zhao Qihong, Feng Huanqing, Harris Lyndsay, Wang Minghui

Abstract excerpt

Genomic copy number alteration and allelic imbalance are distinct features of cancer cells, and recent advances in the genotyping technology have greatly boosted the research in the cancer genome. However, the complicated nature of tumor usually hampers the dissection of the SNP arrays. In this study, we describe a bioinformatic tool, named GIANT, for genome-wide identification of somatic aberrations from paired...

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Identifiers

PMID: 24498045
DOI: 10.1371/journal.pone.0087212
PMCID: PMC3907544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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