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Article

Involvement of the SLIT/ROBO pathway in follicle development in the fetal ovary

9 Nov 2009

Abstract excerpt

In humans and domestic mammals, pivotal processes in ovary development, including primordial follicle assembly, occur prenatally. These events are essential for determining fertility in adult life; however, they remain poorly understood at the mechanistic level. In mammals, the SLITs (SLIT1, SLIT2 and SLIT3) and their ROBO (ROBO1, ROBO2, ROBO3/RIG-1 and ROBO4/MAGIC ROBO) receptors regulate neural, leukocyte,...

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PMID: 19900988
DOI: 10.1530/rep-09-0182

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