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Article

Expression of the repulsive SLIT/ROBO pathway in the human endometrium and Fallopian tube.

Molecular human reproduction - 1 Dec 2010

Duncan W C, McDonald S E, Dickinson R E, Shaw J L V, Lourenco P C, Wheelhouse N, Lee K-F, Critchley H O D, Horne A W

Abstract excerpt

We investigated whether the repulsive SLIT/ROBO pathway is expressed in the endometrium and is negatively regulated during implantation. We also examined whether deficient expression in the Fallopian tube (FT) may predispose to ectopic pregnancy (EP). Endometrium (n = 21) and FT (n = 17) were collected across the menstrual cycle from fertile women with regular cycles. Decidualized endometrium (n = 6) was obtained...

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Source

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Identifiers

PMID: 20651036
DOI: 10.1093/molehr/gaq055
PMCID: PMC2992050

Genes

ROBO1
ROBO2
ROBO3
SLIT1
SLIT2
SLIT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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