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Article

FAS-670A/G polymorphism: A biomarker for the metastasis of nasopharyngeal carcinoma in a Chinese population.

Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2010

Zhu Qingyao, Wang Tao, Ren Jinghua, Hu Kai, Liu Wei, Wu Gang

Abstract excerpt

BACKGROUND: FAS-670 A/G single nucleotide polymorphism has been demonstrated to affect the expression of FAS gene by altering the transcriptional activity of FAS gene promoter. Downregulation of FAS with resultant resistance to death signals has been found in many cancers. We carried out a case-control study to investigate the biological significance of this polymorphism in nasopharyngeal carcinoma (NPC)....

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Source

Identifiers

PMID: 19895798
DOI: 10.1016/j.cca.2009.10.024

Genes

FAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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