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Article

Functional polymorphisms in FAS and FASL contribute to risk of squamous cell carcinoma of the larynx and hypopharynx in a Chinese population.

Gene - 25 Jul 2013

Wang Jiwen, Gao Jia, Li Yingjie, Zhao Xiaoxia, Gao Wei, Peng Li, Yan Dangui, Liu Lisheng, Li Dongmei, Wei Lili, Qi Jun, Zhou Changchun

Abstract excerpt

Accumulating evidences indicate that the functional FAS-1377G>A, -670A>G and FASL-844T>C polymorphisms affect the risk of several kinds of cancers. However, their roles in the development of larynx and hypopharynx squamous cell carcinoma (SCC) were still unknown in the Chinese. In the current study, we examined whether these functional genetic variants were associated with the risk of larynx and hypopharynx...

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Source

Identifiers

PMID: 23618817
DOI: 10.1016/j.gene.2013.04.034

Genes

FAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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