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Article

Rgg-Associated SHP Signaling Peptides Mediate Cross-Talk in Streptococci

11 Jun 2013

Abstract excerpt

We described a quorum-sensing mechanism in the streptococci genus involving a short hydrophobic peptide (SHP), which acts as a pheromone, and a transcriptional regulator belonging to the Rgg family. The shp/rgg genes, found in nearly all streptococcal genomes and in several copies in some, have been classified into three groups. We used a genetic approach to evaluate the functionality of the SHP/Rgg...

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PMID: 23776602
DOI: 10.1371/journal.pone.0066042

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