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Article

A locus of group A streptococcus involved in invasive disease and DNA transfer

1 Oct 2002

Abstract excerpt

Group A streptococcus (GAS) causes diseases ranging from benign to severe infections such as necrotizing fasciitis (NF). The reasons for the differences in severity of streptococcal infections are unexplained. We developed the polymorphic-tag-lengths-transposon-mutagenesis (PTTM) method to identify virulence genes in vivo. We applied PTTM on an emm14 strain isolated from a patient with NF and screened for mutants...

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Identifiers

PMID: 12366833
DOI: 10.1046/j.1365-2958.2002.03127.x

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