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Article

Genetic polymorphisms of drug-metabolizing enzymes and anti-TB drug-induced hepatitis.

Pharmacogenomics - 1 Nov 2009

Kim Sang-Heon, Kim Sang-Hoon, Bahn Joon-Woo, Kim Yoon-Keun, Chang Yoon-Seok, Shin Eun-Soon, Kim Youn-Seup, Park Jae-Seuk, Kim Bo-Hyung, Jang In-Jin, Song Junghan, Kim Seung-Hyun, Park Hae-Sim, Min Kyung-Up, Jee Young-Koo

Abstract excerpt

AIMS: Although some genetic risk factors have been reported for the development of hepatitis due to anti-TB drugs, an extensive candidate gene approach evaluating drug-metabolizing enzymes has not been attempted. This study aimed to investigate the association of genetic polymorphisms in drug-metabolizing enzymes with anti-TB drug-induced hepatitis. MATERIALS & METHODS: We compared genotype distributions of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Arylamine N-Acetyltransferase

Share to Chemical and Drug Induced Liver Injury

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Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 19891553
DOI: 10.2217/pgs.09.100

Genes

NAT2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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