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Novel landscape of HLA‐G isoforms expressed in clear cell renal cell carcinoma patients

17 Aug 2017

Abstract excerpt

Immune checkpoints are powerful inhibitory molecules that promote tumor survival. Their blockade is now recognized as providing effective therapeutic benefit against cancer. Human leukocyte antigen G (HLA-G), a recently identified immune checkpoint, has been detected in many types of primary tumors and metastases, in malignant effusions as well as on tumor-infiltrating cells, particularly in patients with clear...

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PMID: 28815885
DOI: 10.1002/1878-0261.12119

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