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Article

Analysis of the viral elements required in the nuclear import of HIV-1 DNA.

Journal of virology - 1 Jan 2010

Rivière Lise, Darlix Jean-Luc, Cimarelli Andrea

Abstract excerpt

HIV-1 possesses an exquisite ability to infect cells independently from their cycling status by undergoing an active phase of nuclear import through the nuclear pore. This property has been ascribed to the presence of karyophilic elements present in viral nucleoprotein complexes, such as the matrix protein (MA); Vpr; the integrase (IN); and a cis-acting structure present in the newly synthesized DNA, the DNA...

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Identifiers

PMID: 19889772
DOI: 10.1128/JVI.01952-09
PMCID: PMC2798343

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Source receipt: pubmed, retrieved 7 Sept 2026.

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