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Article

BosR (BB0647) governs virulence expression in Borrelia burgdorferi

2 Nov 2009

Abstract excerpt

Summary Borrelia burgdorferi (Bb), the Lyme disease spirochaete, encodes a potential ferric uptake regulator (Fur) homologue, BosR (BB0647). Thus far, a role for BosR in Bb metabolism, gene regulation or pathogenesis has not been determined, largely due to the heretofore inability to inactivate bosR in low-passage, infectious Bb isolates. Herein, we report the generation of the first bosR-deficient mutant in a...

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PMID: 19889086
DOI: 10.1111/j.1365-2958.2009.06945.x

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BosR (BB0647) governs virulence expression in Borrelia burgdorferiPMID 19889086Read ↗

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