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Article

Transcriptomic insights on the virulence-controlling CsrA, BadR, RpoN, and RpoS regulatory networks in the Lyme disease spirochete.

PloS one - 1 Jan 2018

Arnold William K, Savage Christina R, Lethbridge Kathryn G, Smith Trever C, Brissette Catherine A, Seshu Janakiram, Stevenson Brian

Abstract excerpt

Borrelia burgdorferi, the causative agent of Lyme disease, survives in nature through a cycle that alternates between ticks and vertebrates. To facilitate this defined lifestyle, B. burgdorferi has evolved a gene regulatory network that ensures transmission between those hosts, along with specific adaptations to niches within each host. Several regulatory proteins are known to be essential for the bacterium to...

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Source

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Identifiers

PMID: 30161198
DOI: 10.1371/journal.pone.0203286
PMCID: PMC6117026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Transcriptomic insights on the virulence-controlling CsrA, BadR, RpoN, and RpoS regulatory networks in the Lyme disease spirochete.PMID 30161198Read ↗

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