Article

Positive feedback regulation between RpoS and BosR in the Lyme disease pathogen

2024-09-15

Abstract excerpt

<h4>ABSTRACT</h4> In Borrelia burgdorferi , the Lyme disease pathogen, differential gene expression is primarily controlled by the alternative sigma factor RpoS (σ S ). Understanding how RpoS levels are regulated is crucial for elucidating how B. burgdorferi is maintained throughout its enzootic cycle. Our recent studies have shown that a homolog of Fur/PerR repressor/activator, BosR, functions as an RNA-bindi...

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Literature Corpus work: 26e5197a-7d4d-5781-994c-ab44d4285dd7
DOI: 10.1101/2024.09.14.613071

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