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Article

Melanocortin Receptors as Novel Effectors of Macrophage Responses in Inflammation

1 Jan 2011

Abstract excerpt

Macrophages have crucial functions in initiating the inflammatory reaction in a strict temporal and spatial manner to provide a "clear-up" response required for resolution. Hormonal peptides such as melanocortins modulate macrophage reactivity and attenuate inflammation ranging from skin inflammation to joint disease and reperfusion injury. The melanocortins (e.g., adrenocorticotrophin, ACTH and αMSH) elicit...

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Identifiers

PMID: 22566831
DOI: 10.3389/fimmu.2011.00041

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