Article
Proopiomelanocortin (POMC): the cutaneous roles of its melanocortin products and receptors.
Clinical and experimental dermatology - 1 May 2006
Millington G W M
Abstract excerpt
The precursor protein proopiomelanocortin (POMC) produces many biologically active peptides via a series of enzymatic steps in a tissue-specific manner, yielding the melanocyte-stimulating hormones (MSHs), corticotrophin (ACTH) and beta-endorphin. The gene for alpha-MSH is encoded for by the POMC gene, but alpha-MSH cannot be produced from POMC gene transcription and translation without these specific...
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