Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The TolC protein of Legionella pneumophila plays a major role in multi-drug resistance and the early steps of host invasion.

PloS one - 4 Nov 2009

Ferhat Mourad, Atlan Danièle, Vianney Anne, Lazzaroni Jean-Claude, Doublet Patricia, Gilbert Christophe

Abstract excerpt

Pneumonia associated with Iegionnaires's disease is initiated in humans after inhalation of contaminated aerosols. In the environment, Legionella pneumophila is thought to survive and multiply as an intracellular parasite within free-living amoeba. In the genome of L. pneumophila Lens, we identified a unique gene, tolC, encoding a protein that is highly homologous to the outer membrane protein TolC of Escherichia...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Outer Membrane Proteins
Share to Drug Resistance, Multiple

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Genetic Complementation Test

Share to Legionella pneumophila

Share to Multidrug Resistance-Associated Proteins

Share to Reactive Oxygen Species

Share to U937 Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 19888467
DOI: 10.1371/journal.pone.0007732
PMCID: PMC2766832

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The TolC protein of Legionella pneumophila plays a major role in multi-drug resistance and the early steps of host invasion.PMID 19888467Read ↗

Significant role for ladC in initiation of Legionella pneumophila infection.Semantic proximity Read ↗

Deletion of TolC orthologs in Francisella tularensis identifies roles in multidrug resistance and virulence.Semantic proximity Read ↗

Proteome Exploration of Legionella pneumophila To Identify Novel Therapeutics: a Hierarchical Subtractive Genomics and Reverse Vaccinology ApproachSemantic proximity Read ↗

The <i>Escherichia coli</i> TolC efflux pump protein is immunogenic and elicits protective antibodiesSemantic proximity Read ↗

Virulence Properties of the Legionella Pneumophila Cell EnvelopeSemantic proximity Read ↗

The CpxRA two-component system contributes to Legionella pneumophila virulence.Semantic proximity Read ↗

Structure, Function and Regulation of Outer Membrane Proteins Involved in Drug Transport in Enterobactericeae: the OmpF/C – TolC CaseSemantic proximity Read ↗

A conserved OmpA-like protein in Legionella pneumophila required for efficient intracellular replication.Semantic proximity Read ↗

The Legionella pneumophila Dot/Icm-secreted effector PlcC/CegC1 together with PlcA and PlcB promotes virulence and belongs to a novel zinc metallophospholipase C family present in bacteria and fungi.Semantic proximity Read ↗

Legionella pneumophila Type IV Effectors YlfA and YlfB Are SNARE-Like Proteins that Form Homo- and Heteromeric Complexes and Enhance the Efficiency of Vacuole Remodeling.Semantic proximity Read ↗

Characterization of TolC efflux pump proteins from Pasteurella multocida.Semantic proximity Read ↗

The TolC protein of Escherichia coli serves as a cell-surface receptor for the newly characterized TLS bacteriophage.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.