Article
Cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations and risk for pancreatic adenocarcinoma.
Cancer - 1 Jan 2010
McWilliams Robert R, Petersen Gloria M, Rabe Kari G, Holtegaard Leonard M, Lynch Pamela J, Bishop Michele D, Highsmith W Edward
Abstract excerpt
BACKGROUND: Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene are common in white persons and are associated with pancreatic disease. The purpose of this case-control study was to determine whether CFTR mutations confer a higher risk of pancreatic cancer. METHODS: In a case-control study, the authors compared the rates of 39 common cystic fibrosis-associated CFTR mutations between...
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