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Article

CFTR, SPINK1, CTRC and PRSS1 variants in chronic pancreatitis: is the role of mutated CFTR overestimated?

Gut - 1 Apr 2013

Rosendahl Jonas, Landt Olfert, Bernadova Jana, Kovacs Peter, Teich Niels, Bödeker Hans, Keim Volker, Ruffert Claudia, Mössner Joachim, Kage Andreas, Stumvoll Michael, Groneberg David, Krüger Renate, Luck Werner, Treiber Matthias, Becker Michael, Witt Heiko

Abstract excerpt

OBJECTIVE: In chronic pancreatitis (CP), alterations in several genes have so far been described, but only small cohorts have been extensively investigated for all predisposing genes. DESIGN: 660 patients with idiopathic or hereditary CP and up to 1758 controls were enrolled. PRSS1, SPINK1 and CTRC were analysed by DNA sequencing, and cystic fibrosis transmembrane conductance regulator (CFTR) by melting curve...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22427236
DOI: 10.1136/gutjnl-2011-300645

Genes

CFTR
CTRC
PRSS1
SPINK1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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