Mutations of the cystic fibrosis gene in patients with chronic pancreatitis.

doi:10.1056/NEJM199809033391001

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Article

Mutations of the cystic fibrosis gene in patients with chronic pancreatitis.

The New England journal of medicine - 3 Sept 1998

Sharer N, Schwarz M, Malone G, Howarth A, Painter J, Super M, Braganza J

Abstract excerpt

BACKGROUND: The pancreatic lesions of cystic fibrosis develop in utero and closely resemble those of chronic pancreatitis. Therefore, we hypothesized that mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene may be more common than expected among patients with chronic...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Chlorides
Chronic Disease
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
Female
Genotype
Humans
Introns
Male
Middle Aged
Mutation
Nasal Mucosa
Pancreatitis
Phenotype

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