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Article

Orbitofrontal cortex and drug use during adolescence: role of prenatal exposure to maternal smoking and BDNF genotype.

Archives of general psychiatry - 1 Nov 2009

Lotfipour Shahrdad, Ferguson Eamonn, Leonard Gabriel, Perron Michel, Pike Bruce, Richer Louis, Séguin Jean R, Toro Roberto, Veillette Suzanne, Pausova Zdenka, Paus Tomás

Abstract excerpt

CONTEXT: Prenatal exposure to maternal cigarette smoking (PEMCS) may affect brain development and behavior in adolescent offspring. OBJECTIVE: To evaluate the involvement of the orbitofrontal cortex (OFC) in mediating the relationship between PEMCS and substance use. DESIGN: Cross-sectional analyses from the Saguenay Youth Study aimed at evaluating the effects of PEMCS on brain development and behavior among...

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Source

Identifiers

PMID: 19884612
DOI: 10.1001/archgenpsychiatry.2009.124

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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