Article

Shared neurobiological mechanisms and behavioral strategies contribute to elevated substance use disorder risk in comorbid autism and ADHD

2026-03-10

Abstract excerpt

<title>Abstract</title> <p>The clinical landscape of neurodevelopmental psychiatry has fundamentally shifted following the formal recognition that autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) frequently cooccur. While historically viewed as distinct entities, the comorbid "AuDHD" phenotype is now understood to represent a unique neurobiological state characterized by high sus...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 34910a9b-a617-5a34-b728-0d749d4263fa
DOI: 10.21203/rs.3.rs-9065458/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Shared neurobiological mechanisms and behavioral strategies contribute to elevated substance use disorder risk in comorbid autism and ADHDDOI 10.21203/rs.3.rs-9065458/v1Read

Behavioral disinhibition and the development of early-onset addiction: common and specific influences.Semantic proximity Read

Autism Spectrum Disorders and Drug Addiction: Common Pathways, Common Molecules, Distinct Disorders?Semantic proximity Read

Addiction Risk Polymorphisms Links Autism Spectrum Disorder with Reward Deficiency Syndrome: Insights from GWAS and Pharmacogenomic Meta AnalysesSemantic proximity Read

Hatching the behavioral addiction egg: Reward Deficiency Solution System (RDSS)™ as a function of dopaminergic neurogenetics and brain functional connectivity linking all addictions under a common rubricSemantic proximity Read

Shaping vulnerability to addiction - the contribution of behavior, neural circuits and molecular mechanisms.Semantic proximity Read

Neuroscience and Genetic: Can They Be a Faustian Bargain for Addictive Behaviours Research and Treatment?Semantic proximity Read

Modelling Differential Vulnerability to Substance Use Disorder in Rodents: Neurobiological Mechanisms.Semantic proximity Read

Substance use in youth at genetic and clinical high risk for psychosisSemantic proximity Read

Brain networks underlying vulnerability and resilience to drug addiction.Semantic proximity Read

Genetic overlap and causality between substance use disorder and attention-deficit and hyperactivity disorder.Semantic proximity Read

Neurobiological contributions to addiction: a narrative review of adolescent and adult vulnerabilities.Semantic proximity Read

ADHD and autism: differential diagnosis or overlapping traits? A selective review.Semantic proximity Read