Article
Effect of interclonal heterogeneity on the progressive, confluence-mediated acquisition of the focus-forming phenotype in NIH-3T3 populations.
Cancer research - 1 Feb 1991
Grundel R, Rubin H
Abstract excerpt
Confluence is an agent that promotes the progressive acquisition of the focus forming phenotype in clones of cells within NIH-3T3 populations. This conclusion is based on four results. (a) Even in cultures which have been confluent for more than 2 weeks without making foci, some cells in those cultures have been affected by the confluent state and will make foci if replated and allowed to grow into new saturated...
Topics
- Cell Aggregation
- Cell Count
- Cell Division
- Cell Line, Transformed
- Fibroblasts
- Phenotype