Adaptation and selection as factors in the spontaneous transformation of NIH-3T3 cells.

doi:10.1093/carcin/13.10.1873

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Article

Adaptation and selection as factors in the spontaneous transformation of NIH-3T3 cells.

Carcinogenesis - 1 Oct 1992

Grundel R, Rubin H

Abstract excerpt

The effect of calf serum (CS) concentration on the spontaneous transformation of NIH-3T3 cells was investigated. Maintenance of NIH-3T3 cell populations in media containing a low concentration of calf serum (2% CS) increased the proportion of spontaneously transformed cells appearing within a pop...

Topics

3T3 Cells
Adaptation, Physiological
Animals
Cell Division
Cell Transformation, Neoplastic
Mice
Phenotype
Selection, Genetic

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