Article
NK cell activation by KIR-binding antibody 1-7F9 and response to HIV-infected autologous cells in viremic and controller HIV-infected patients.
Clinical immunology (Orlando, Fla.) - 1 Feb 2010
Johansson Susanne E, Hejdeman Bo, Hinkula Jorma, Johansson Maria H, Romagné François, Wahren Britta, Wagtmann Nicolai R, Kärre Klas, Berg Louise
Abstract excerpt
Natural killer (NK) cells may be protective in HIV infection and are inhibited by killer cell immunoglobulin-like receptors (KIRs) interacting with MHC class I molecules, including HLA-C. Retention of HLA-C despite downregulation of other MHC class I molecules on HIV infected cells might protect...
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