Article
[Mutations of the hemagglutinin gene of H9N2 subtype avian influenza viruses under selective pressure of antibody].
Wei sheng wu xue bao = Acta microbiologica Sinica - 1 Jul 2009
Lou Benhong, Zhu Xiutong, Sun Beibei, Cui Zhizhong
Abstract excerpt
OBJECTIVE: To understand mutations of avian influenza virus (AIV) under the antibody selective pressures. METHODS: We continuously passed an H9N2-AIV strain LG1 in embryos with or without maternal antibody to LG1 in 6 separate serials. At the 10th, 20th, 30th, 40th and 50th passages in each serial, H9 hemagglutinatin gene (HA) sequences were determined and compared to the original LG1 strain. RESULTS: Only...
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