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Article

Epitope variation in the Newcastle disease virus HN gene under antibody immune selective pressure in cell culture.

Science China. Life sciences - 1 May 2011

Gong YanYan, Cui ZhiZhong

Abstract excerpt

The influence of antibody immune selective pressure on Newcastle disease virus (NDV) HN and F gene mutations was studied in cell cultures. NDV field strain TZ060107 was inoculated into chicken embryo fibroblast cells and continuously passaged with (group A) or without (group B) anti-NDV monospecific serum. Each group contained three independent passage series. HN and F genes were amplified and sequenced for the...

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PMID: 21455691
DOI: 10.1007/s11427-011-4161-2

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