Article
[An analysis of the potential areas of recombination in the hemagglutinin genes of animal influenza viruses in relation to their adaptation to a new host--man].
Voprosy virusologii - 1 Jan 2000
Blinov V M, Kiselev O I, Resenchuk S M, Brovkin A I, Bukrinskaia A G, Sandakhchiev L S
Abstract excerpt
The authors tried to decode the mechanism of influenza viruses species adaptation in the process of host changing. The functionally important replacement in the surface pocket domains were revealed, particularly in the conservative region 221-241, involving fibronectin-like part. Close replacements were revealed in the region 141-161. The method of construction of heteroduplexes between hemagglutinin RNA of duck,...
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