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Article

Cloning, nucleotide sequence, and characterization of mtr, the structural gene for a tryptophan-specific permease of Escherichia coli K-12.

Journal of bacteriology - 1 Jan 1991

Heatwole V M, Somerville R L

Abstract excerpt

The mtr gene of Escherichia coli K-12 encodes an L-tryptophan-specific permease. This gene was originally identified through the isolation of mutations in the 69-min region of the chromosome, closely linked to argG. Cells with lesions in mtr display a phenotype of 5-methyltryptophan resistance. The mtr gene was cloned by using the mini-Mu system. The amino acid sequence of Mtr (414 codons), deduced by DNA...

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Identifiers

PMID: 1987112
DOI: 10.1128/jb.173.1.108-115.1991
PMCID: PMC207163

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